Nanopore-based sensing for biomarker detection: from fundamental principles to translational diagnostics

Abstract Nanopore-based sensing has emerged as a transformative approach for biomarker detection, offering label-free, single-molecule analysis with exceptional sensitivity and specificity. By monitoring ionic current modulations as individual molecules traverse biological or solid-state nanopores,...

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Bibliographic Details

Published in:	Journal of Nanobiotechnology
Main Authors:	Narlawar Sagar Shrikrishna, Sonu Gandhi
Format:	Article
Language:	English
Published:	BMC 2025-10-01
Subjects:	Nanopore biosensing Single-molecule detection Biological nanopores Solid state nanopores Biomarker diagnostics Point-of-care detection
Online Access:	https://doi.org/10.1186/s12951-025-03762-8