Circulating CXCR5⁺CD4⁺ T Follicular-Like Helper Cell and Memory B Cell Responses to Human Papillomavirus Vaccines.

Through the interaction of T follicular helper (Tfh) cells and B cells, efficacious vaccines can generate high-affinity, pathogen-neutralizing antibodies, and memory B cells. Using CXCR5, CXCR3, CCR6, CCR7, PD1, and ICOS as markers, Tfh-like cells can be identified in the circulation and be classifi...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Ken Matsui, Joseph W Adelsberger, Troy J Kemp, Michael W Baseler, Julie E Ledgerwood, Ligia A Pinto
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2015-01-01
Online Access:	https://doi.org/10.1371/journal.pone.0137195