Opportunities for and Challenges of Conducting Indirect Treatment Comparisons and Meta-Analyses for Vaccines in Post-EU HTA Regulation Era

The dynamic nature of infectious diseases introduces inherent challenges to the design of vaccine clinical trials, which consequently makes vaccine indirect treatment comparisons (ITCs) and meta-analyses (MAs) more challenging compared with regular pharmaceuticals. However, comparisons of efficacy a...

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Bibliographic Details

Published in:	Journal of Market Access & Health Policy
Main Authors:	Charlotte Graham, Erin Barker, Joe Moss, Emily Gregg, Rachael McCool, Nathalie Largeron, Mélanie Trichard, José Bartelt-Hofer, Maribel Tribaldos
Format:	Article
Language:	English
Published:	MDPI AG 2025-06-01
Subjects:	indirect treatment comparison meta-analysis comparative effectiveness vaccine health technology assessment EU Regulation on Health Technology Assessment
Online Access:	https://www.mdpi.com/2001-6689/13/2/31