Autocrine STAT3 activation in HPV positive cervical cancer through a virus-driven Rac1-NFκB-IL-6 signalling axis.

Persistent human papillomavirus (HPV) infection is the leading cause of cervical cancer. Although the fundamental link between HPV infection and oncogenesis is established, the specific mechanisms of virus-mediated transformation are not fully understood. We previously demonstrated that the HPV enco...

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Bibliographic Details
Published in:PLoS Pathogens
Main Authors: Ethan L Morgan, Andrew Macdonald
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-06-01
Online Access:https://doi.org/10.1371/journal.ppat.1007835