Adoptive cellular immunotherapy for solid neoplasms beyond CAR-T

Abstract In recent decades, immune checkpoint blockade and chimeric antigen receptor T cell (CAR-T) therapy are two milestone achievements in clinical immunotherapy. However, both show limited efficacies in most solid neoplasms, which necessitates the exploration of new immunotherapeutic modalities....

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Bibliographic Details

Published in:	Molecular Cancer
Main Authors:	Qiaofei Liu, Jiayi Li, Huaijin Zheng, Sen Yang, Yuze Hua, Nan Huang, Jorg Kleeff, Quan Liao, Wenming Wu
Format:	Article
Language:	English
Published:	BMC 2023-02-01
Subjects:	Adoptive cell therapy Immune checkpoint Chimeric antigen receptor TCR Natural killer cell Macrophage
Online Access:	https://doi.org/10.1186/s12943-023-01735-9