Biologically informed deep learning for explainable epigenetic clocks

Abstract Ageing is often characterised by progressive accumulation of damage, and it is one of the most important risk factors for chronic disease development. Epigenetic mechanisms including DNA methylation could functionally contribute to organismal aging, however the key functions and biological...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Aurel Prosz, Orsolya Pipek, Judit Börcsök, Gergely Palla, Zoltan Szallasi, Sandor Spisak, István Csabai
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-01-01
Online Access:	https://doi.org/10.1038/s41598-023-50495-5