A transient resistance to blood-stage malaria in interferon-γ-deficient mice through impaired production of host cells preferred by malaria parasites

IFN-γ plays both pathological and protective roles during blood-stage malaria. One of its pathological roles is its contribution to anemia by suppressing erythropoiesis. Here, to evaluate the effects of IFN-γ-mediated alterations in erythropoiesis on the course of malaria infection, mice deficient i...

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Bibliographic Details

Published in:	Frontiers in Microbiology
Main Authors:	Hiroko eOkada, Kazutomo eSuzue, Takashi eImai, Tomoyo eTaniguchi, Chikako eShimokawa, Risa eOnishi, Jun eHirata, Hajime eHISAEDA
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2015-06-01
Subjects:	Erythropoiesis Malaria Reticulocytes IFN-γ host–parasite relationship
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00600/full