Autophagy Inhibition with Chloroquine Increased Pro-Apoptotic Potential of New Aziridine-Hydrazide Hydrazone Derivatives against Glioblastoma Cells

Tumor therapy escape due to undesired side effects induced by treatment, such as prosurvival autophagy or cellular senescence, is one of the key mechanisms of resistance that eventually leads to tumor dormancy and recurrence. Glioblastoma is the most frequent and practically incurable neoplasm of th...

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Bibliographic Details

Published in:	Cells
Main Authors:	Monika Witusik-Perkowska, Pola Głowacka, Adam M. Pieczonka, Ewa Świderska, Agnieszka Pudlarz, Michał Rachwalski, Julia Szymańska, Magdalena Zakrzewska, Dariusz J. Jaskólski, Janusz Szemraj
Format:	Article
Language:	English
Published:	MDPI AG 2023-07-01
Subjects:	autophagy apoptosis tumor therapy escape glioblastoma aziridine derivatives hydrazide hydrazone derivatives
Online Access:	https://www.mdpi.com/2073-4409/12/14/1906