An Inhibitory Role for Human CD96 Endodomain in T Cell Anti-Tumor Responses

Immune checkpoint blockade (ICB) therapy involves the inhibition of immune checkpoint regulators which reverses their limitation of T cell anti-tumor responses and results in long-lasting tumor regression. However, poor clinical response or tumor relapse was observed in some patients receiving such...

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Bibliographic Details

Published in:	Cells
Main Authors:	Chelsia Qiuxia Wang, Fong Chan Choy, Arleen Sanny, Takashi Murakami, Andy Hee-Meng Tan, Kong-Peng Lam
Format:	Article
Language:	English
Published:	MDPI AG 2023-01-01
Subjects:	CD96 immune checkpoint immunotherapy immunologic receptors T cell cytotoxicity
Online Access:	https://www.mdpi.com/2073-4409/12/2/309