Recombinant ROP6 protein expressed in Saccharomyces cerevisiae INVSc1 cells induced strong immune response and provided significant protection against toxoplasmosis

Abstract Toxoplasma gondii is a zoonotic parasite that infects almost all warm-blooded animals and humans and results in serious health problems. There is no drug treatment for chronic toxoplasmosis. Thus, a safe and protective vaccine is required by the community to combat against the chronic infec...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Tuğba Karakavuk, Muhammet Karakavuk, Ceren Gül, Hüseyin Can, Aytül Gül, Sedef Erkunt Alak, Aysu Değirmenci Döşkaya, Seren Kaplan, İrem Yavuz, Hasan Akbaba, Gülşah Erel Akbaba, Didem Şen Karaman, Ahmet Efe Köseoğlu, Tolga Ovayurt, Adnan Yüksel Gürüz, Cemal Ün, Ayşe Gülten Kantarcı, Mert Döşkaya
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-09-01
Subjects:	Toxoplasma gondii Rhoptry ROP6 Recombinant protein vaccine Saccharomyces cerevisiae
Online Access:	https://doi.org/10.1038/s41598-025-14988-9