Unmasking culprits: novel analysis identifies complement factors as potential therapeutic targets to mitigate inflammation during children's heart surgery

Abstract Background Cardiopulmonary bypass (CPB) causes systemic inflammation during pediatric cardiac surgery, which can contribute to post-operative organ dysfunction and prolonged recovery. This study aims to identify key inflammatory mediators related to this clinically significant immunologic r...

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Bibliographic Details

Published in:	European Journal of Medical Research
Main Authors:	Joel Bierer, Roger Stanzel, Mark Henderson, John Sapp, Pantelis Andreou, Jean S. Marshall, David Horne
Format:	Article
Language:	English
Published:	BMC 2024-12-01
Subjects:	Pediatric cardiac surgery Congenital heart disease Cardiopulmonary bypass Complement Inflammation
Online Access:	https://doi.org/10.1186/s40001-024-02156-0