Human Placental Mesenchymal Stem Cells Relieve Primary Sclerosing Cholangitis via Upregulation of TGR5 in Mdr2−/− Mice and Human Intrahepatic Cholangiocyte Organoid Models

Primary sclerosing cholangitis (PSC) is a biliary disease accompanied by chronic inflammation of the liver and biliary stricture. Mesenchymal stem cells (MSCs) are used to treat liver diseases because of their immune regulation and regeneration-promoting functions. This study was performed to explor...

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Bibliographic Details

Published in:	Research
Main Authors:	Qigu Yao, Wenyi Chen, Yingduo Yu, Feiqiong Gao, Jiahang Zhou, Jian Wu, Qiaoling Pan, Jinfeng Yang, Lingling Zhou, Jiong Yu, Hongcui Cao, Lanjuan Li
Format:	Article
Language:	English
Published:	American Association for the Advancement of Science (AAAS) 2023-01-01
Online Access:	https://spj.science.org/doi/10.34133/research.0207