TDRD6 mediates early steps of spliceosome maturation in primary spermatocytes.

Tudor containing protein 6 (TDRD6) is a male germ line-specific protein essential for chromatoid body (ChB) structure, elongated spermatid development and male fertility. Here we show that in meiotic prophase I spermatocytes TDRD6 interacts with the key protein arginine methyl transferase PRMT5, whi...

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Bibliographic Details

Published in:	PLoS Genetics
Main Authors:	Müge Akpınar, Mathias Lesche, Grigorios Fanourgakis, Jun Fu, Konstantinos Anastassiadis, Andreas Dahl, Rolf Jessberger
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2017-03-01
Online Access:	http://europepmc.org/articles/PMC5358835?pdf=render