Identification of a Novel Mutation in the SERPINE1 Gene Causing Clinical Hyperfibrinolysis in English Springer Spaniel Dogs

ABSTRACT Background A 7‐month‐old female spayed English Springer Spaniel (ESS) was evaluated for spontaneous hemoperitoneum. Hyperfibrinolysis was identified on thromboelastography. Hypothesis/Objectives To identify a genetic mutation causing congenital hyperfibrinolysis in the proband and evaluate...

Full description

Bibliographic Details

Published in:	Journal of Veterinary Internal Medicine
Main Authors:	Kelley Kilpatrick, Jonah N. Cullen, Farah F. Almeer, LeeAnn Higgins, Todd Markowski, Marjory Brooks, Steven G. Friedenberg, Molly Racette
Format:	Article
Language:	English
Published:	Wiley 2025-07-01
Subjects:	coagulation delayed postoperative hemorrhage plasminogen activator inhibitor‐1 whole genome sequencing
Online Access:	https://doi.org/10.1111/jvim.70150