Unfair competition governs the interaction of pCPI-17 with myosin phosphatase (PP1-MYPT1)

The small phosphoprotein pCPI-17 inhibits myosin light-chain phosphatase (MLCP). Current models postulate that during muscle relaxation, phosphatases other than MLCP dephosphorylate and inactivate pCPI-17 to restore MLCP activity. We show here that such hypotheses are insufficient to account for the...

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Bibliographic Details

Published in:	eLife
Main Authors:	Joshua J Filter, Byron C Williams, Masumi Eto, David Shalloway, Michael L Goldberg
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2017-04-01
Subjects:	smooth muscle contraction/relaxation myosin phosphatase CPI-17 unfair competition
Online Access:	https://elifesciences.org/articles/24665