Applying Next-Generation Sequencing to Track HIV-1 Drug Resistance Mutations Circulating in Portugal

Background: The global scale-up of antiretroviral treatment (ART) offers significant health benefits by suppressing HIV-1 replication and increasing CD4 cell counts. However, incomplete viral suppression poses a potential threat for the emergence of drug resistance mutations (DRMs), limiting ART opt...

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Bibliographic Details

Published in:	Viruses
Main Authors:	Victor Pimentel, Marta Pingarilho, Cruz S. Sebastião, Mafalda Miranda, Fátima Gonçalves, Joaquim Cabanas, Inês Costa, Isabel Diogo, Sandra Fernandes, Olga Costa, Rita Corte-Real, M. Rosário O. Martins, Sofia G. Seabra, Ana B. Abecasis, Perpétua Gomes
Format:	Article
Language:	English
Published:	MDPI AG 2024-04-01
Subjects:	HIV-1 drug resistance INSTIs NGS Portugal Europe
Online Access:	https://www.mdpi.com/1999-4915/16/4/622