CD74 is expressed in a subset of pediatric acute myeloid leukemia patients and is a promising target for therapy: a report from the Children’s Oncology Group

As curative therapies for pediatric AML remain elusive, identifying potential new treatment targets is vital. We assessed the cell surface expression of CD74, also known as the MHC-II invariant chain, by multidimensional flow cytometry in 973 patients enrolled in the Children’s Oncology Group AAML1...

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Bibliographic Details
Published in:Haematologica
Main Authors: Andrew J. Menssen, Chad A. Hudson, Todd Alonzo, Robert Gerbing, Laura Pardo, Amanda Leonti, Jacqueline A. Cook, Fan-Chi Hsu, Loren L. Lott, Fangyan Dai, Collette Fearing, Keely Ghirardelli, Tiffany Hylkema, Katherine Tarlock, Keith R. Loeb, Edward A. Kolb, Todd Cooper, Jessica Pollard, Denise A. Wells, Michael R. Loken, Richard Aplenc, Soheil Meshinchi, Lisa Eidenschink Brodersen
Format: Article
Language:English
Published: Ferrata Storti Foundation 2024-02-01
Online Access:https://haematologica.org/article/view/11426