Case report: STRN3-NTRK3 fusion in uterine sarcoma with spleen metastasis: a new variant in the spectrum of NTRK-rearranged tumors

Neurotrophic tyrosine receptor kinase (NTRK) fusions are infrequent genetic events that can occur in various tumor types. Specifically, NTRK-rearranged sarcoma has been observed in pediatric mesenchymal tumors and, to a lesser extent, in adult mesenchymal tumors like fibrosarcoma. Recently, NTRK-rea...

Full description

Bibliographic Details

Published in:	Frontiers in Medicine
Main Authors:	Piergiuseppe Colombo, Giuseppina Adriana Buonamassa, Anita Giulianini, Letizia Hassan, Noemi Rudini, Antonio Rizzo, Enrico Cavallo, Carlo Carnaghi, Salumeh Goudarzi, Sebastiano Mongiovì, Sarah Pafumi, Stefano Marletta
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-11-01
Subjects:	neurotrophic tyrosine receptor kinase (NTRK) uterine sarcoma STRN3-NTRK3 rearranged tumors targeted therapy
Online Access:	https://www.frontiersin.org/articles/10.3389/fmed.2024.1448491/full