Regulation of autophagy, lipid metabolism, and neurodegenerative pathology by heparan sulfate proteoglycans

Heparan sulfate modified proteins or proteoglycans (HSPGs) are an abundant class of cell surface and extracellular matrix molecules. They serve important co-receptor functions in the regulation of signaling as well as membrane trafficking. Many of these activities directly affect processes associate...

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Bibliographic Details

Published in:	Frontiers in Genetics
Main Authors:	Nicholas Schultheis, Robert Becker, Gelila Berhanu, Alexander Kapral, Matthew Roseman, Shalini Shah, Alyssa Connell, Scott Selleck
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-01-01
Subjects:	autophagy lipid metabolism mitochondria heparan sulfate proteoglycans presenilin
Online Access:	https://www.frontiersin.org/articles/10.3389/fgene.2022.1012706/full