Association of attenuated leptin signaling pathways with impaired cardiac function under prolonged high-altitude hypoxia

Abstract Cardiovascular function and adipose metabolism were markedly influenced under high altitudes. However, the interplay between adipokines and heart under hypoxia remains to be elucidated. We aim to explore alterations of adipokines and underlying mechanisms in regulating cardiac function unde...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Jianan Wang, Shiying Liu, Lihong Sun, Zhanping Kong, Jiamin Chai, Jigang Wen, Xuan Tian, Nan Chen, Chengli Xu
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-05-01
Subjects:	Hypoxia Antarctica Humans Rats Leptin Cardiovascular diseases
Online Access:	https://doi.org/10.1038/s41598-024-59559-6