The circular RNA circDLG1 promotes gastric cancer progression and anti-PD-1 resistance through the regulation of CXCL12 by sponging miR-141-3p

Abstract Background Dysregulation of circular RNAs (circRNAs) plays an important role in the development of gastric cancer; thus, revealing the biological and molecular mechanisms of abnormally expressed circRNAs is critical for identifying novel therapeutic targets in gastric cancer. Methods A circ...

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Bibliographic Details
Published in:Molecular Cancer
Main Authors: Dong-Liang Chen, Hui Sheng, Dong-Sheng Zhang, Ying Jin, Bai-Tian Zhao, Nuo Chen, Kang Song, Rui-Hua Xu
Format: Article
Language:English
Published: BMC 2021-12-01
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Online Access:https://doi.org/10.1186/s12943-021-01475-8