Mendelian randomization evidence based on European ancestry for the causal effects of leukocyte telomere length on prostate cancer

Abstract Background Several lines of evidence suggest that leukocyte telomere length (LTL) can affect the development of prostate cancer (PC). Methods Here, we employed single nucleoside polymorphisms (SNPs) as instrumental variables (IVs) for LTL (n = 472,174) and conducted Mendelian randomization...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Human Genomics
المؤلفون الرئيسيون: Xinrui Wu, Cong Hu, Tianyang Wu, Xinxing Du, Zehong Peng, Wei Xue, Yonghui Chen, Liang Dong
التنسيق: مقال
اللغة:الإنجليزية
منشور في: BMC 2024-06-01
الوصول للمادة أونلاين:https://doi.org/10.1186/s40246-024-00622-8