Identification of Pre-symptomatic Gene Signatures That Predict Resilience to Cognitive Decline in the Genetically Diverse AD-BXD Model

Across the population, individuals exhibit a wide variation of susceptibility or resilience to developing Alzheimer’s disease (AD). Identifying specific factors that promote resilience would provide insight into disease mechanisms and nominate potential targets for therapeutic intervention. Here, we...

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Bibliographic Details

Published in:	Frontiers in Genetics
Main Authors:	Sarah M. Neuner, Sarah E. Heuer, Ji-Gang Zhang, Vivek M. Philip, Catherine C. Kaczorowski
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-02-01
Subjects:	resilience network analysis Alzheimer’s susceptibility genetics transcriptomics
Online Access:	https://www.frontiersin.org/article/10.3389/fgene.2019.00035/full