Sonic Hedgehog Ligand: A Role in Formation of a Mesenchymal Niche in Human Pancreatic Ductal Adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is characterised by desmoplasia, thought to support progression and chemotherapeutic resistance. The Hedgehog pathway is known to play an important role in this cancer. While the upregulation of Sonic hedgehog (Shh) in the epithelium of PDAC is known, we inves...

詳細記述

書誌詳細
出版年:Cells
主要な著者: Francesca Saini, Richard H. Argent, Anna M. Grabowska
フォーマット: 論文
言語:英語
出版事項: MDPI AG 2019-05-01
主題:
オンライン・アクセス:https://www.mdpi.com/2073-4409/8/5/424