Dysfunction of Calcyphosine-Like gene impairs retinal angiogenesis through the MYC axis and is associated with familial exudative vitreoretinopathy

Familial exudative vitreoretinopathy (FEVR) is a severe genetic disorder characterized by incomplete vascularization of the peripheral retina and associated symptoms that can lead to vision loss. However, the underlying genetic causes of approximately 50% of FEVR cases remain unknown. Here, we repor...

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Bibliographic Details

Published in:	eLife
Main Authors:	Wenjing Liu, Shujin Li, Mu Yang, Jie Ma, Lu Liu, Ping Fei, Qianchun Xiang, Lulin Huang, Peiquan Zhao, Zhenglin Yang, Xianjun Zhu
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2024-09-01
Subjects:	angiogenesis familial exudative vitreoretinopathy CAPSL MYC knockout models
Online Access:	https://elifesciences.org/articles/96907