Fluorinated polyamidoamine dendrimer-mediated miR-23b delivery for the treatment of experimental rheumatoid arthritis in rats

Delivery of anti-inflammatory microRNA (miRNA) could be beneficial for inflammatory diseases such as rheumatoid arthritis (RA). Here the authors show that a fluorinated polyamidoamine dendrimer nanoparticle delivers miR-23b to affected RA joints and reduces inflammation, joint damage and synovial ce...

詳細記述

書誌詳細
出版年:Nature Communications
主要な著者: Haobo Han, Jiakai Xing, Wenqi Chen, Jiaxin Jia, Quanshun Li
フォーマット: 論文
言語:英語
出版事項: Nature Portfolio 2023-02-01
オンライン・アクセス:https://doi.org/10.1038/s41467-023-36625-7