Bromodomain-Containing 4 Is a Positive Regulator of Interleukin-34 Production in the Gut

Experimental evidence suggests that, in the inflamed gut of inflammatory bowel disease (IBD) patients, interleukin-34 (IL-34) triggers detrimental signaling pathways. Factors/mechanisms regulating IL-34 production in IBD remain poorly characterized. Bromodomain-containing 4 (BRD4), a transcriptional...

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Bibliographic Details

Published in:	Cells
Main Authors:	Eleonora Franzè, Federica Laudisi, Rachele Frascatani, Lorenzo Tomassini, Elena De Cristofaro, Carmine Stolfi, Giovanni Monteleone
Format:	Article
Language:	English
Published:	MDPI AG 2024-10-01
Subjects:	colitis inflammatory cytokines mucosal inflammation JQ1
Online Access:	https://www.mdpi.com/2073-4409/13/20/1698