Role of hepatitis B virus non-structural protein HBx on HBV replication, interferon signaling, and hepatocarcinogenesis

Hepatitis B, a global health concern caused by the hepatitis B virus (HBV), infects nearly 2 billion individuals worldwide, as reported by the World Health Organization (WHO). HBV, a hepatotropic DNA virus, predominantly targets and replicates within hepatocytes. Those carrying the virus are at incr...

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Bibliographic Details

Published in:	Frontiers in Microbiology
Main Authors:	Fei Wang, Hongxiao Song, Fengchao Xu, Jing Xu, Le Wang, Fan Yang, Yujia Zhu, Guangyun Tan
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-12-01
Subjects:	HBx HBV interferon (IFN) HCC ISGs (IFN-stimulated genes)
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2023.1322892/full