METTL5 regulates SEPHS2-mediated selenoprotein synthesis to promote multiple myeloma survival and progression

Abstract The abnormal expression of m6A methyltransferase is a significant factor in the occurrence and progression of tumors. The 18S ribosomal RNA (rRNA) m6A methyltransferase Methyltransferase-like 5 (METTL5) is upregulated in various cancers, leading to adverse prognosis by abnormally regulating...

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Bibliographic Details

Published in:	Cell Death and Disease
Main Authors:	Junyao Jiang, Fangmin Zhong, Zuomiao Xiao, Fangyi Yao, Jing Liu, Meiyong Li, Huan Zeng, Yuxiang Qiu, Jing Zhang, Haibin Zhang, Shuqi Li, Ting huang, Wenli Feng, Zhenglan Huang, Bo Huang, Xiaozhong Wang
Format:	Article
Language:	English
Published:	Nature Publishing Group 2025-08-01
Online Access:	https://doi.org/10.1038/s41419-025-07904-6