Ovarian Cancer-Cell Pericellular Hyaluronan Deposition Negatively Impacts Prognosis of Ovarian Cancer Patients

Background: Hyaluronan (HA), a component of the extracellular matrix, is frequently increased under pathological conditions including cancer. Not only stroma cells but also cancer cells themselves synthesize HA, and the interaction of HA with its cognate receptors promotes malignant progression and...

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Bibliographic Details

Published in:	Biomedicines
Main Authors:	Leticia Oliveira-Ferrer, Barbara Schmalfeldt, Johannes Dietl, Catharina Bartmann, Udo Schumacher, Christine Stürken
Format:	Article
Language:	English
Published:	MDPI AG 2022-11-01
Subjects:	ovarian cancer stromal hyaluronan tumor-associated hyaluronan staining pattern hyaluronan-related enzymes
Online Access:	https://www.mdpi.com/2227-9059/10/11/2944