Ovarian Cancer-Cell Pericellular Hyaluronan Deposition Negatively Impacts Prognosis of Ovarian Cancer Patients

Background: Hyaluronan (HA), a component of the extracellular matrix, is frequently increased under pathological conditions including cancer. Not only stroma cells but also cancer cells themselves synthesize HA, and the interaction of HA with its cognate receptors promotes malignant progression and...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:	Biomedicines
المؤلفون الرئيسيون:	Leticia Oliveira-Ferrer, Barbara Schmalfeldt, Johannes Dietl, Catharina Bartmann, Udo Schumacher, Christine Stürken
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	MDPI AG 2022-11-01
الموضوعات:	ovarian cancer stromal hyaluronan tumor-associated hyaluronan staining pattern hyaluronan-related enzymes
الوصول للمادة أونلاين:	https://www.mdpi.com/2227-9059/10/11/2944

مواد مشابهة

Targeting Hyaluronan Synthesis in Cancer: A Road Less Travelled
حسب: Theodoros Karalis
منشور في: (2023-12-01)

Differential Regulation of Hyaluronan Synthesis by Three Isoforms of Hyaluronan Synthases in Mammalian Cells
حسب: Jie Wang, وآخرون
منشور في: (2024-12-01)

Salicylate suppresses the oncogenic hyaluronan network in metastatic breast cancer cells
حسب: Theodoros T. Karalis, وآخرون
منشور في: (2020-05-01)

Hyaluronan synthase 1 (HAS1): A mysterious enzyme with unexpected functions
حسب: Hanna eSiiskonen, وآخرون
منشور في: (2015-02-01)

Hyaluronan-based pericellular matrix: substrate electrostatic charges and early cell adhesion events
حسب: C Fotia, وآخرون
منشور في: (2013-01-01)

Expression and molecular characterization of an intriguing hyaluronan synthase (HAS) from the symbiont “Candidatus Mycoplasma liparidae” in snailfish
حسب: Lulu Guo, وآخرون
منشور في: (2025-04-01)

Glucocorticoids Directly Affect Hyaluronan Production of Orbital Fibroblasts; A Potential Pleiotropic Effect in Graves’ Orbitopathy
حسب: Erika Galgoczi, وآخرون
منشور في: (2022-12-01)

The Effect of Mechanical Stress on Hyaluronan Fragments’ Inflammatory Cascade: Clinical Implications
حسب: Antonio Stecco, وآخرون
منشور في: (2023-11-01)

‘Two-faces’ of hyaluronan, a dynamic barometer of disease progression in tumor microenvironment
حسب: Ying Liu, وآخرون
منشور في: (2023-01-01)

Hyaluronan accumulation is associated with reduced hyaluronidase expression in renal cell carcinoma, with CD44, HAS1, and HYAL2 emerging as prognostic markers
حسب: Otto Jokelainen, وآخرون
منشور في: (2025-07-01)

Hyaluronan breakdown by snake venom hyaluronidases: From toxins delivery to immunopathology
حسب: Felipe Silva de França, وآخرون
منشور في: (2023-03-01)

Increased RHAMM expression relates to ovarian cancer progression
حسب: Stephanie T. Buttermore, وآخرون
منشور في: (2017-09-01)

Hyaluronan Metabolism is Associated with DNA Repair Genes in Breast and Colorectal Cancer. Screening of Potential Progression Markers Using qPCR
حسب: Ina Sevic, وآخرون
منشور في: (2020-06-01)

Reparative Effects of Astaxanthin-Hyaluronan Nanoaggregates against Retrorsine-CCl4-Induced Liver Fibrosis and Necrosis
حسب: Yi Jhen Wu, وآخرون
منشور في: (2018-03-01)

Bone quality relies on hyaluronan synthesis – Insights from mice with complete knockout of hyaluronan synthase expression
حسب: A. Saalbach, وآخرون
منشور في: (2024-12-01)

Remodelling of the bone marrow microenvironment by stromal hyaluronan modulates the malignancy of breast cancer cells
حسب: Xiaoyan Chen, وآخرون
منشور في: (2020-06-01)

The Hyaluronan Pericellular Coat and Cold Atmospheric Plasma Treatment of Cells
حسب: Claudia Bergemann, وآخرون
منشور في: (2020-07-01)

Effect of diclofenac etalhyaluronate (SI-613) on the production of high molecular weight sodium hyaluronate in human synoviocytes
حسب: Tomochika Kisukeda, وآخرون
منشور في: (2019-05-01)

A comprehensive review on microbial hyaluronan-degrading enzymes: from virulence factors to biotechnological tools
حسب: Jia-Yu Jiang, وآخرون
منشور في: (2024-12-01)

To compare the effect of the local delivery of hyaluronan as an adjunct to scaling and root planing versus scaling and root planing alone in the treatment of chronic periodontitis
حسب: Srishti Anil Shah, وآخرون
منشور في: (2016-01-01)

Clinical significance of hyaluronan levels and its pro-osteogenic effect on mesenchymal stromal cells in myelodysplastic syndromes
حسب: Cheng-Ming Fei, وآخرون
منشور في: (2018-08-01)

Hyaluronan in COVID-19: a matrix for understanding lung disease
حسب: Rebecca J. Dodd, وآخرون
منشور في: (2024-12-01)

Hyaluronan - a functional and structural sweet spot in the tissue microenvironment
حسب: James eMonslow, وآخرون
منشور في: (2015-05-01)

The effect of aminooxy-linkers’ structure on the mechanical properties of hyaluronan-oxime hydrogels
حسب: Petra Sedova, وآخرون
منشور في: (2022-03-01)

The hyaluronan-related genes HAS2, HYAL1-4, PH20 and HYALP1 are associated with prognosis, cell viability and spheroid formation capacity in ovarian cancer
حسب: Jette Riecks, وآخرون
منشور في: (2022-06-01)

Developing Fluorescent Hyaluronan Analogs for Hyaluronan Studies
حسب: Shi Ke, وآخرون
منشور في: (2012-02-01)

Loss of Endothelial Glycocalyx Hyaluronan Impairs Endothelial Stability and Adaptive Vascular Remodeling after Arterial Ischemia
حسب: Gangqi Wang, وآخرون
منشور في: (2020-03-01)

ROS-Mediated Fragmentation Alters the Effects of Hyaluronan on Corneal Epithelial Wound Healing
حسب: Xiao Lin, وآخرون
منشور في: (2023-09-01)

Hyaluronan-Binding Protein Promotes Fibroblast Transformation and Heart Failure by Modulating the STAT5A–MMP13 Pathway
حسب: Hui Yan, وآخرون
منشور في: (2025-05-01)

Epidermal Hyaluronan in Barrier Alteration-Related Disease
حسب: Céline Evrard, وآخرون
منشور في: (2021-11-01)

Densification: Hyaluronan Aggregation in Different Human Organs
حسب: Antonio Stecco, وآخرون
منشور في: (2022-04-01)

Key Role of Hyaluronan Metabolism for the Development of Brain Metastases in Triple-Negative Breast Cancer
حسب: Fabienne Hamester, وآخرون
منشور في: (2022-10-01)

Unique hyaluronan structure of expanded oocyte-cumulus extracellular matrix in ovarian follicles
حسب: Nagyova Eva, وآخرون
منشور في: (2024-01-01)

Hyaluronan-Based Nanohydrogels as Effective Carriers for Transdermal Delivery of Lipophilic Agents: Towards Transdermal Drug Administration in Neurological Disorders
حسب: Seong Uk Son, وآخرون
منشور في: (2017-12-01)

Hyaluronan-Cholesterol Nanogels for the Enhancement of the Ocular Delivery of Therapeutics
حسب: Nicole Zoratto, وآخرون
منشور في: (2021-10-01)

Distribution of versican and hyaluronan in the mouse uterus during decidualization
حسب: S. San Martin, وآخرون
منشور في: (2003-08-01)

Detection and identification of hyaluronan oligosaccharides derived from free-radical depolymerization via reverse-phase ion-pair HPLC/mass spectrometry
حسب: Zhiqing Tian, وآخرون
منشور في: (2025-03-01)

The Degradation of Hyaluronan in the Skin
حسب: Petra Žádníková, وآخرون
منشور في: (2022-02-01)

Hyaluronan: Metabolism and Function
حسب: Takashi Kobayashi, وآخرون
منشور في: (2020-11-01)

Derivatization of Hyaluronan to Target Neuroblastoma and Neuroglioma Expressing CD44
حسب: Giau Van Vo, وآخرون
منشور في: (2024-06-01)