Aliphatic Quaternary Ammonium Functionalized Nanogels for Gene Delivery

Gene therapy is a promising treatment for hereditary diseases, as well as acquired genetic diseases, including cancer. Facing the complicated physiological and pathological environment in vivo, developing efficient non-viral gene vectors is needed for their clinical application. Here, poly(<i>...

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Bibliographic Details

Published in:	Pharmaceutics
Main Authors:	Huaiying Zhang, Damla Keskin, Willy H. de Haan-Visser, Guangyue Zu, Patrick van Rijn, Inge S. Zuhorn
Format:	Article
Language:	English
Published:	MDPI AG 2021-11-01
Subjects:	nanogels gene delivery endosomal escape quaternization aliphatic chains
Online Access:	https://www.mdpi.com/1999-4923/13/11/1964