The acid ceramidase/ceramide axis controls parasitemia in Plasmodium yoelii-infected mice by regulating erythropoiesis

Acid ceramidase (Ac) is part of the sphingolipid metabolism and responsible for the degradation of ceramide. As bioactive molecule, ceramide is involved in the regulation of many cellular processes. However, the impact of cell-intrinsic Ac activity and ceramide on the course of Plasmodium infection...

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Bibliographic Details
Published in:eLife
Main Authors: Anne Günther, Matthias Hose, Hanna Abberger, Fabian Schumacher, Ylva Veith, Burkhard Kleuser, Kai Matuschewski, Karl Sebastian Lang, Erich Gulbins, Jan Buer, Astrid M Westendorf, Wiebke Hansen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-09-01
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Online Access:https://elifesciences.org/articles/77975