Dual targeting with 224Ra/212Pb-conjugates for targeted alpha therapy of disseminated cancers: A conceptual approach

Metastases are the primary cause of death among cancer patients and efficacious new treatments are sorely needed. Targeted alpha-emitting radiopharmaceuticals that are highly cytotoxic may fulfill this critical need. The focus of this paper is to describe and explore a novel technology that may impr...

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Bibliographic Details

Published in:	Frontiers in Medicine
Main Authors:	Asta Juzeniene, Vilde Yuli Stenberg, Øyvind Sverre Bruland, Mona-Elisabeth Revheim, Roy Hartvig Larsen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-01-01
Subjects:	cancer lead-212 radiopharmaceutical radium-224 radium-223 targeted radionuclide therapy (TRT)
Online Access:	https://www.frontiersin.org/articles/10.3389/fmed.2022.1051825/full