Folic acid supplementation in children with sickle cell disease: study protocol for a double-blind randomized cross-over trial

Abstract Background Sickle cell disease (SCD) is a genetic disorder which causes dysfunctional red blood cells (RBC) and is thought to increase requirements for folate, an essential B vitamin, due to increased RBC production and turnover in the disease. High-dose supplementation with 1–5 mg/d folic...

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發表在:	Trials
Main Authors:	Brock A. Williams, Heather McCartney, Erin Adams, Angela M. Devlin, Joel Singer, Suzanne Vercauteren, John K. Wu, Crystal D. Karakochuk
格式:	Article
語言:	英语
出版:	BMC 2020-06-01
主題:	Sickle cell disease Pediatrics Nutrition Folic acid Micronutrient supplementation Randomized control trial
在線閱讀:	http://link.springer.com/article/10.1186/s13063-020-04540-7