Automized inline monitoring in perfused mammalian cell culture by MIR spectroscopy without calibration model building

Abstract Process Analytical Technologies (PATs) are taking a key role in the run for automatization in the biopharmaceutical industry. Spectroscopic methods such as Raman spectroscopy or mid‐infrared (MIR) spectroscopy are getting more recognition in the recent years for inline monitoring of bioproc...

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Bibliographic Details

Published in:	Engineering in Life Sciences
Main Authors:	Hannah Marienberg, Nicole Desch, Vitalii Mozin, Lorenz Sykora‐Mirle, Anja Müller, Andreas Roth, Mathias Käfer, Rüdiger Neef
Format:	Article
Language:	English
Published:	Maximum Academic Press 2024-03-01
Subjects:	analytics CHO MIR PAT perfusion spectroscopy
Online Access:	https://doi.org/10.1002/elsc.202300237