Plasmodium falciparum CRK4 links early mitotic events to the onset of S-phase during schizogony

ABSTRACT Plasmodium falciparum proliferates through schizogony in the clinically relevant blood stage of infection. During schizogony, consecutive rounds of DNA replication and nuclear division give rise to multinucleated stages before cellularization occurs. Although these nuclei reside in a shared...

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Bibliographic Details

Published in:	mBio
Main Authors:	Marta Machado, Severina Klaus, Darius Klaschka, Julien Guizetti, Markus Ganter
Format:	Article
Language:	English
Published:	American Society for Microbiology 2023-08-01
Subjects:	malaria cell cycle Plasmodium falciparum kinase microtubules DNA replication
Online Access:	https://journals.asm.org/doi/10.1128/mbio.00779-23