Effects of ZSET1446/ST101 on Cognitive Deficits and Amyloid β Deposition in the Senescence Accelerated Prone Mouse Brain

The senescence accelerated prone mouse strain 8 (SAMP8) develops age-related deficits in learning and memory. Effects of the azaindolizinone derivative ZSET1446/ST101, a newly synthesized cognitive enhancer, on cognitive impairment and deposition of amyloid β (Aβ) were assessed in the SAMP8. ZSET144...

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Bibliographic Details
Published in:Journal of Pharmacological Sciences
Main Authors: Yoshimasa Yamaguchi, Kenichi Saito, Toshiyuki Matsuno, Kentaro Takeda, Masataka Hino
Format: Article
Language:English
Published: Elsevier 2012-01-01
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319305080