Late-stage diversification strategy for the synthesis of peptide acids and amides using hydrazides

Aim: Modification of the C-terminus of a peptide to improve its properties, particularly after constructing the peptide chain, has great promise in the development of peptide therapeutics. This study discusses the development of a late-stage diversification method for synthesizing peptide acids and...

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Bibliographic Details

Published in:	Exploration of Drug Science
Main Authors:	Shoko Tanaka, Mizuki Kanno, Yosuke Tashiro, Tetsuo Narumi, Nobuyuki Mase, Kohei Sato
Format:	Article
Language:	English
Published:	Open Exploration 2023-10-01
Subjects:	late-stage diversification peptide hydrazide peptide acid peptide amide antimicrobial peptide
Online Access:	https://www.explorationpub.com/uploads/Article/A100823/100823.pdf