Material Stiffness in Cooperation with Macrophage Paracrine Signals Determines the Tenogenic Differentiation of Mesenchymal Stem Cells

Abstract Stiffness is an important physical property of biomaterials that determines stem cell fate. Guiding stem cell differentiation via stiffness modulation has been considered in tissue engineering. However, the mechanism by which material stiffness regulates stem cell differentiation into the t...

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Bibliographic Details

Published in:	Advanced Science
Main Authors:	Renwang Sheng, Jia Liu, Wei Zhang, Yifan Luo, Zhixuan Chen, Jiayu Chi, Qingyun Mo, Mingyue Wang, Yuzhi Sun, Chuanquan Liu, Yanan Zhang, Yue Zhu, Baian Kuang, Chunguang Yan, Haoyang Liu, Ludvig J. Backman, Jialin Chen
Format:	Article
Language:	English
Published:	Wiley 2023-06-01
Subjects:	macrophage polarization proteomics stiffness stem cell tenogenic differentiation
Online Access:	https://doi.org/10.1002/advs.202206814