Thrombotic Microangiopathy as an Emerging Complication of Viral Vector–Based Gene Therapy

Gene therapy has brought tremendous hope for patients with severe life-threatening monogenic diseases. Although studies have shown the efficacy of gene therapy, serious adverse events have also emerged, including thrombotic microangiopathy (TMA) following viral vector–based gene therapy. In this rev...

Full description

Bibliographic Details

Published in:	Kidney International Reports
Main Authors:	Nora Schwotzer, Carine El Sissy, Isabelle Desguerre, Véronique Frémeaux-Bacchi, Laurent Servais, Fadi Fakhouri
Format:	Article
Language:	English
Published:	Elsevier 2024-07-01
Subjects:	complement gene therapy immune response thrombotic microangiopathy
Online Access:	http://www.sciencedirect.com/science/article/pii/S2468024924016474