CYP3A Excipient-Based Microemulsion Prolongs the Effect of Magnolol on Ischemia Stroke Rats

Magnolol, which is a CYP3A substrate, is a well-known agent that can facilitate neuroprotection and reduce ischemic brain damage. However, a well-controlled release formulation is needed for the effective delivery of magnolol due to its poor water solubility. In this study, we have developed a formu...

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Bibliographic Details

Published in:	Pharmaceutics
Main Authors:	Jiun-Wen Guo, Chih-Cheng Chien, Jiann-Hwa Chen
Format:	Article
Language:	English
Published:	MDPI AG 2020-08-01
Subjects:	magnolol microemulsion neuroprotection effect brain ischemic CYP3A
Online Access:	https://www.mdpi.com/1999-4923/12/8/737