Stem cell therapies for biological repair in osteonecrosis: advances, challenges, and clinical insights

Osteonecrosis is a bone condition that begins as an ischemic process and can progress to subchondral collapse and premature joint degeneration in untreated cases. Conventional treatments offer physical or symptomatic relief but do not address the underlying physiological deficiencies. Regenerative t...

Full description

Bibliographic Details

Published in:	Frontiers in Medicine
Main Authors:	Deliang Cheng, Xuehai Ou, Jiafeng Long, Changming Zheng, Shaoyan Shi
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2026-06-01
Subjects:	angiogenesis bone regeneration extracellular vesicles mesenchymal stem cells osteonecrosis regenerative medicine
Online Access:	https://www.frontiersin.org/articles/10.3389/fmed.2026.1772819/full