Early Gray Matter Volume Loss in MAPT H1H1 de Novo PD Patients: A Possible Association With Cognitive Decline

The MAPT H1 haplotype has been identified as a predictor of cognitive decline in Parkinson's disease (PD). However, its underlying pathological mechanisms have not been fully established. In this work, using a cohort of 120 de novo PD patients with preserved cognition from the Parkinson's...

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Bibliographic Details

Published in:	Frontiers in Neurology
Main Authors:	Frederic Sampedro, Juan Marín-Lahoz, Saul Martínez-Horta, Javier Pagonabarraga, Jaime Kulisevsky
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-05-01
Subjects:	MAPT T1-MRI cognitive decline Parkinson's disease gray matter volume
Online Access:	https://www.frontiersin.org/article/10.3389/fneur.2018.00394/full