Multiply restimulated human cord blood-derived Tregs maintain stabilized phenotype and suppressive function and predict their therapeutic effects on autoimmune diabetes

Abstract Background Regulatory T cells (Tregs) are involved in the maintenance of immune homeostasis and immune regulation. Clinical trials on the adoptive transfer of Tregs have been ongoing for > 10 years. However, many unresolved issues remain in the production of readymade Treg products and s...

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出版年:	Diabetology & Metabolic Syndrome
主要な著者:	Yuanjie Bi, Ran Kong, Yani Peng, Donghua Cai, Yu Zhang, Fan Yang, Xia Li, Wen Deng, Fang Liu, Binbin He, Chuqing Cao, Chao Deng, Xiaohan Tang, Li Fan, Haibo Yu, Zhiguang Zhou
フォーマット:	論文
言語:	英語
出版事項:	BMC 2024-03-01
主題:	Regulatory T cells Umbilical cord blood Cell proliferation Autoimmune diabetes Cell therapy
オンライン･アクセス:	https://doi.org/10.1186/s13098-024-01277-0