Efficacy of trimetazidine for myocardial ischemia-reperfusion injury in rat models: a systematic review and meta-analysis

Context Trimetazidine (TMZ) is used as a medication for ischemic heart disease treatment. Recently, several animal models have been studied in relation to the research on myocardial ischemia-reperfusion injury (MIRI) treatment. In this study, we conducted a meta-analysis of TMZ in rat MIRI models to...

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Bibliographic Details

Published in:	PeerJ
Main Authors:	Xiaobin Zhang, Zhanhui Duan, Yanpu Yu, Chunjing Li, Mingyao Hao, Yuning Ma, Yuxia Ma, Dongqing Du
Format:	Article
Language:	English
Published:	PeerJ Inc. 2025-06-01
Subjects:	Myocardial ischemia-reperfusion injury Trimetazidine Superoxide dismutase Creatine kinase isoenzyme Myocardial infarct size Systematic review
Online Access:	https://peerj.com/articles/19515.pdf