Streptolysin S is required for Streptococcus pyogenes nasopharyngeal and skin infection in HLA-transgenic mice.

Streptococcus pyogenes is a human-specific pathogen that commonly colonizes the upper respiratory tract and skin, causing a wide variety of diseases ranging from pharyngitis to necrotizing fasciitis and toxic shock syndrome. S. pyogenes has a repertoire of secreted virulence factors that promote inf...

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Bibliographic Details

Published in:	PLoS Pathogens
Main Authors:	Blake A Shannon, Jacklyn R Hurst, Ronald S Flannagan, Heather C Craig, Aanchal Rishi, Katherine J Kasper, Stephen W Tuffs, David E Heinrichs, John K McCormick
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2024-03-01
Online Access:	https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1012072&type=printable