Association of ORMDL3 and IKZF3 expression with the IL2RA rs2104286 risk variant in relapsing-remitting multiple sclerosis

The genetic variant IL2RA rs2104286 (A>G) is strongly associated with multiple sclerosis (MS) risk. It modulatesIL-2 signaling, thereby influencing the expression of lymphocyte function-related genes ORMDL3 and IKZF3 that areimplicated in multiple sclerosis pathogenesis. This study aimed to i...

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发表在:	Archives of Biological Sciences
Main Authors:	Stefanović Milan, Stojković Ljiljana, Kolić Ivana, Đorđević Ana, Dinčić Evica, Stanković Aleksandra, Živković Maja
格式:	文件
语言:	英语
出版:	University of Belgrade, University of Novi Sad 2026-01-01
主题:	multiple sclerosis il2ra rs2104286 ormdl3 ikzf3
在线阅读:	https://doiserbia.nb.rs/img/doi/0354-4664/2026/0354-46642500036S.pdf