Decreased Equilibrative Nucleoside Transporter 1 (ENT1) Activity Contributes to the High Extracellular Adenosine Levels in Mesenchymal Glioblastoma Stem-Like Cells

Glioblastoma multiforme is one of the most malignant types of cancer. This is mainly due to a cell subpopulation with an extremely aggressive potential, called glioblastoma stem-like cells (GSCs). These cells produce high levels of extracellular adenosine which has been associated with increased che...

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Bibliographic Details

Published in:	Cells
Main Authors:	Sebastián Alarcón, María de los Ángeles Toro, Carolina Villarreal, Rómulo Melo, Rodrigo Fernández, Angel Ayuso Sacido, Daniel Uribe, Rody San Martín, Claudia Quezada
Format:	Article
Language:	English
Published:	MDPI AG 2020-08-01
Subjects:	adenosine glioblastoma glioblastoma stem-like cells (GSCs) equilibrative nucleoside transporter 1 (ENT1).
Online Access:	https://www.mdpi.com/2073-4409/9/8/1914