Plasmodium falciparum pfhrp2 and pfhrp3 gene deletions among patients enrolled at 100 health facilities throughout Tanzania: February to July 2021

Abstract Plasmodium falciparum with the histidine rich protein 2 gene (pfhrp2) deleted from its genome can escape diagnosis by HRP2-based rapid diagnostic tests (HRP2-RDTs). The World Health Organization (WHO) recommends switching to a non-HRP2 RDT for P. falciparum clinical case diagnosis when pfhr...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Eric Rogier, Nastassia Battle, Catherine Bakari, Misago D. Seth, Douglas Nace, Camelia Herman, Achut Barakoti, Rashid A. Madebe, Celine I. Mandara, Beatus M. Lyimo, David J. Giesbrecht, Zachary R. Popkin-Hall, Filbert Francis, Daniel Mbwambo, Issa Garimo, Sijenunu Aaron, Abdallah Lusasi, Fabrizio Molteni, Ritha Njau, Jane A. Cunningham, Samwel Lazaro, Ally Mohamed, Jonathan J. Juliano, Jeffrey A. Bailey, Venkatachalam Udhayakumar, Deus S. Ishengoma
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-04-01
Subjects:	Plasmodium falciparum Tanzania RDT pfhrp2 pfhrp3 Gene deletion
Online Access:	https://doi.org/10.1038/s41598-024-58455-3